报告题目：The Role of SR-B1/hCLA-1, a receptor for HDL, in Atherosclerosis.
报告人: Dr. Yu Xiao
报告时间：2015年06月24日（周三）13:30
报告地点：新威尼斯v0008独墅湖校区医学楼403-3120
报告人简介：
Dr. Yu Xiao received her Bachelor degree of clinical medicine from Nanjing University of Traditional Medicine in 1995, then worked as an internal doctor at Suzhou Traditional Medical Hospital. In 2007, Dr. Yu received her M.D. and Ph.D. from Kagawa University, Japan，and undertook research work as a Research Assistant in Kagawa University. Afterwards she joined IBMS of Soochow University in 2008 and promoted to Associate Researcher in 2013. Dr. Yu has focused on lipoprotein metabolism，atherosclerosis and diabetes. Her previous reporter showed CaMKK/KIV cascade participated both in glucose upregulation of insulin gene( Diabetes 2004) and GLUT2 gene regulated by Exendin-4 (Metabolism 2011)；SR-B1,as a HDL receptor,was reduced by angiotensinII or hyperglycemia, took part in the development of atherosclerosis(Hypertension 2007); SR-B1 also can be a possible HCV Receptor, decreased its expression by interferon alpha（GUT，2008）. In addition to her research, she has been teaching Medical Immunology to the medical students at Soochow University.
近三年发表的论文：
1.Fukata Y, Yu X, Imachi H, Nishiuchi T, Lyu J, Seo K, Takeuchi A, Iwama H, Masugata H, Hoshikawa H, Hosomi N, Iwasaki Y, Murao K. 17β-Estradiol regulates scavenger receptor class BI gene expression via protein kinase C in vascular endothelial cells. Endocrine. 2014 Aug;46(3):644-50.
2.Yu X, Zhang C, Sun A, Jiang L, Zheng J, You Y, Wu D, Zhou Y. Genetic variations in CD14 promoter and acute lymphoblastic leukemia susceptibility in a Chinese population. DNA Cell Biol. 2012 ;30(10):777-82.
3.Imachi H, Yu X, Nishiuchi T, Miyai Y, Masugata H, Murao K. Raloxifene inhibits menin-dependent estrogen receptor activation in breast cancer cells. J Endocrinol Invest. 2011;34(11):813-5.
4.Yu X,Chen K, Murao K, Imachi H, Li J, Muraoka T, Masugata H, Zhang GX, Kobayashi R, Ishida T, Tokumitsu H.Exendin-4 regulates GLUT2 expression via the CaMKK/CaMKIV pathway in a pancreatic β-cell line. Metabolism. 2011 ;60(4):579-85.