Establishment Cuture and Differentiation of Human Embryonic Stem Cells and appilcation of Human Embryonic Stem Cells in Embryonic Neurotoxicity Test

发布时间:2015-06-23浏览次数:837

报告题目:Establishment Cuture and Differentiation of Human Embryonic Stem Cells and appilcation of Human Embryonic Stem Cells in  Embryonic Neurotoxicity Test

报告人:Boxian Huang Ph.D

报告时间:2015年06月24日(周三)13:30

报告地点:新威尼斯v0008独墅湖校区医学楼403-3120

报告人简介:

      Boxian Huang. In the summer of 2015, he will obtain Ph.D degree from China Pharmaceutical University.

During his Ph.D stage in 2013, he participated in applying for NSFC Project. He also participated in two National Fund Projects, with one in 973 Project and another in NSFC Project.

His mentor in China is Prof. Jiayin Liu, who is very famous in the field of reproductive medicine. His mentor in U.S. is Prof. Wange Lu (study with Nobel Prize Winner: David Baltimore), who is a well-known expert in stem cell research.

Boxian Huang focuses on the model of human embryonic stem cell differentiation into dopamine neuron in China, and finds out that the mechanism of small molecular affects differentiation process. In US, Boxian Huang’s research direction is knocking a huntington gene “HTT” into human embryonic stem cells by CRISPR/CAS9.

During past three years’ study, Boxian Huang published five SCI papers, among which three are listed as the first author, and the other two are as the second author. IF runs almost near fifteen points. By far he has already submitted four papers to professional journals. And in addition, he has also become a reviewer for many journals.

近三年发表论文:

1. Boxian Huang, Chunyan Jiang, Jian Luo, Yugui Cui, Lianju Qin, Jiayin Liu. Maternal exposure of Bisphenol A may increase the risks of fetal origins of Parkinson's disease by down-regulating of the IGF-1 expression in the offspring. Medical Hypotheses. Doi:10.1016/j.mehy.2013.10.023.

2. Boxian Huang, Chunyan Jiang, Aiqin Chen, Yugui Cui, Jiazi Xie, Jiandong Shen, et al. Normal Human Embryonic Stem Cell Lines Were Derived from mosaic trisomy 9. Taiwan Association of Obstetrics and Gynecology. Doi:10.3892/taoj_epub

3. Boxian Huang, Song Ning, Lili Zhuang, Chunyan Jiang, Aiqin Chen, Yugui Cui, Guoping Fan, Lianju Qin, Jiayin Liu. Ethanol Fixed Mouse Embryonic Fibroblasts Maintain the Self-renew and Proliferation of Human Embryonic Stem Cells. PloS One. Doi: 10.1371/journal.pone.0130332

4. Li-Li Zhuang, Bo-Xian Huang, Jie Feng, Liang-Hua Zhu , Rui Jin, Ling-Zhi Qiu, et al. All-trans retinoic acid modulates ORMDL3 expression via transcriptional regulation. PloS One. Doi: 10.1371/journal.pone.0077304

5. Chunyan Jiang, Linbo Cai, Boxian Huang, Juan Dong, Aiqin Chen, Song Ning, et al. Normal Human Embryonic Stem Cell Lines Were Derived from Microsurgical Enucleated Tripronuclear Zygotes. Journal of Cellular Biochemistry. Doi: 10.1002/jcb.24547.